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Recommendations

Best Cannabis for Nausea – Research & Recommendations

November 11, 2025

Looking for a strain to calm a sick stomach? Gotham has done the research and has recommendations for 5 strains that address an upset stomach.

If you find yourself dealing with nausea, interestingly enough cannabis may help your situation. While the idea of being high and nauseous sounds unappealing to some at first glance, research from decades ago suggests that cannabis genuinely is good for dealing with nausea and vomiting. Synthetic cannabinoids were FDA approved for combatting chemotherapy-inducing nausea and vomiting as early as 1985 and recent studies show that whole-plant cannabis may offer superior relief through the entourage effect. Just thinking logically, it makes so much sense that if the synthetic version works for, that the actual plant itself would produce similar if not more effective results. According to Sharkey & Wiley (2016), “the endocannabinoid system is the master regulator of nausea circuits”, with studies within the 15 years showing cannabinoids to be effective for both dealing with the onset of nausea and vomiting and the anticipation of them as well.

THC and CBD are the cannabinoids that work best for dealing with nausea, particularly in combination with each other due to the entourage effect and the main terpenes that work best for dealing with nausea are limonene for it’s gastroprotective effects, beta-caryophyllene for it’s anti-inflammatory effects and pinene for having both. With those in mind, that leads us to our recommendations:

Rythm Jack’s Delight 2g AIO

Jack’s Delight 2g AIO from Rythm is an uplifting sativa with genetics from Jack Herer, a strain rich in pinene and terpinolene with high patient satisfaction scores in clinical studies and Afternoon Delight #4, a balanced hybrid rich in beta-caryophyllene and limonene. With genetics from two strains rich in terpenes perfect for easing nausea, it makes for an excellent option.

Off Hours Cherry Diesel | Cherry Bomb

Off Hours’ Cherry Diesel “Cherry Bomb” live rosin gummies are a hybrid strain with Beta-Caryophyllene and Limonene as its primary terpenes, which provide the anti-inflammatory and gastroprotective effects good for easing the feeling of nausea.

Infused White Widow Ruby Rose Blunt

Ruby Farm’s White Widow Ruby Rose Blunt boasts one of the most highly recommended strains for nausea relief and functionality. The strain has a balanced terp profile and a slight sativa lean, is both euphoric and appetite-stimulating while also being clinically proven to be good for chemotherapy patients, and it’s been a staple in Amsterdam Coffee Shops since the 90s.

Electraleaf Super Mac 3.5g

Electraleaf’s Super Mac 3.5g contains genetics from Super Silver Haze and Lemon Mac with Beta-Caryophyllene, Limonene, and Pinene as its dominant terps, providing a bright citrusy flavor, aromatic notes of lemon and herbs, and uplifting, focusing, and creative effects, while also providing the gastroprotective and anti-inflammatory effects necessary for the desired relief.

Hudson Cannabis Blue Dream Hash

Hudson Cannabis’ Blue Dream Hash features one of the most well known and sought after strains, with the terp profile to fit the bill for nausea relief as well as a full body relaxtion without sedation and a gentle onset highly suitable for those new to cannabis.

As a reminder, dosage is important and consuming too much cannabis can have an adverse effect and increase feelings of nausea. While cannabis doesn’t have the same potential for addiction, overdosing and other various side effects of traditional medications, keep the THC percentage and your dosage relatively low, especially if you have a low tolerance, or else you won’t achieve the desired effect. If you’d like to learn more, check out some of our other blogs:

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